Network-based analysis of vaccine-related associations reveals consistent knowledge with the vaccine ontology

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Network-based analysis of vaccine-related associations reveals consistent knowledge with the vaccine ontology

BACKGROUND Ontologies are useful in many branches of biomedical research. For instance, in the vaccine domain, the community-based Vaccine Ontology (VO) has been widely used to promote vaccine data standardization, integration, and computer-assisted reasoning. However, a major challenge in the VO has been to construct ontologies of vaccine functions, given incomplete vaccine knowledge and incon...

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A major challenge in the vaccine research has been to identify important vaccine-related networks and logically explain the results. In this paper, we showed that networkbased analysis of vaccine-related networks can discover the underlying structure information consistent with that captured by the Vaccine Ontology and propose new hypotheses for vaccine disease or gene associations. First, a va...

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designing an ontology for knowledge discovery in iran’s vaccine

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ژورنال

عنوان ژورنال: Journal of Biomedical Semantics

سال: 2013

ISSN: 2041-1480

DOI: 10.1186/2041-1480-4-33